MEN syndromes

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These are multiple endocrine neoplasias (MEN) that display autosomal dominant inheritance. 
• MEN 1:  the “3 Ps:  parathyroid hyperplasia (100%),  pancreatic endocrine tumors (40–70%),  pituitary adenomas (30–50%) 
• MEN 2:  medullary cell thyroid carcinoma (100%), pheochromocytoma (50%), and the following:
    •   MEN 2a:  parathyroid hyperplasia (80%)   
    •   MEN 2b:  mucosal and bowel neuromas, marfanoid habitus       

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